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Vitamin B12 is essential for the conversion of carbohydrates into glucose, facilitating energy production and alleviating fatigue and lethargy

A 2020 clinical trial found it significantly improved skin elasticity after 12 weeks, with participants reporting reduced wrinkles and better hydration

5-Amino-1MQ alone improved grip strength to a greater degree than rigorous exercise training alone, and combined treatment produced sustained increases in daily running distance that did not taper off in the way exercise-alone groups did, suggesting reduced post-exercise muscle recovery requirement

MEF: mouse embryonic fibroblasts

That gap in data means no responsible recommendation can be made either way