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This raises the question of why activation of NRF2 through KEAP1 carbonylation (227, 228), which may further compromise cellular protection

P1014 Rentea D.-E

Effects on neuronal potassium (K + ) channelsof which four major groups [voltage-gated K + channels (K V ), Ca 2+ -activated K + channels (K Ca ), two-pore K + channels (K 2P ) and inwardly-rectifying K + channels (K ir )] are expressed in peripheral nervesfurther exacerbate altered neuronal excitability in CIPN

In a study in mice, melatonin improved the efficiency of the placenta by increasing the expression of antioxidant enzymes in undernourished pregnancies (117)

In fact, we can make things much worse in the long run for the individual

The finalized protein structures were then converted to pdbqt format using ADT