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Safety and tolerability of increasing doses of CB-839, a first-in-class, orally administered small molecule inhibitor of glutaminase, in solid tumors

Auerdem bring dieses Enzym auch freies Carnitin aus dem Inneren der Mitochondrien zurck in das Zellwasser

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Adverse Reactions/Side Effects Oxalate, urate, or cystine renal stones causing renal tubular obstruction, characterized by costovertebral pain or lower back pain, can occur following large doses of ascorbic acid

(1996): Medial prefrontal cortical D1 receptor modulation of the meso-accumbens dopamine response to stress: an electrochemical study in freely-behaving rats