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Crowe W, Allsopp PJ, Nyland JF, Magee PJ, Strain JJ, Doherty LC, Watson GE, Ball E, Riddell C, Armstrong DJ, Penta K, Todd JJ, Spence T, McSorley EM Toxicology in vitro : an international journal published in association with BIBRA

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In the context of metabolic disorders, studies suggest that melatonin restores the activity of the PI3K/AKT/mechanistic target of rapamycin (mTOR) pathway, reduces insulin receptor substrate-1 (IRS-1) phosphorylation, and increases insulin-like growth factor 1 (IGF-1) activity

doi: 10.1016/j.fochx.2024.102050, 281

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Low levels of glutathione make us susceptible to free radicals that cause cancers, infections, autoimmune diseases, asthma, and neurological conditions such as Parkinsons, MS, and Alzheimers