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b , CRISPR/Cas9 RNPs containing one of four guides delivered to cells by electroporation

Such agents may include, for example, aminoglycoside antibiotics, acetominophen, morphine and other opiates

The raw 16S rRNA sequencing data generated in this study have been deposited in the Genome Sequence Archive (GSA) at the National Genomics Data Center, China National Center for Bioinformation / Beijing Institute of Genomics, Chinese Academy of Sciences, under accession number GSACRA038413

Additionally, this study was also extended to the synthesis of hetero-tetracyclic derivatives containing endocyclic nitrogen atoms

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Future research should focus on understanding the specific role of AST in preventing these diseases and exploring its potential as an adjuvant therapeutic agent in clinical settings