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The pituitary, which was formerly stimulated to produce and secrete GH, now lies dormant due to suppression by the hypothalamus in response to elevated GH (or IGF-1) blood levels from the recombinant product

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Several serious complications such as elevated liver enzymes, SOS, hemorrhagic cystitis, interstitial pneumonia and mucositis have been correlated to high-dose busulphan 10,11,12,15,33

Poor sleep increases the risk of a person developing diabetes (Nga et al, 2024), and people who have diabetes are more likely to experience insomnia than people without diabetes