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Science 347 , 1260419 (2015)

The improved functioning of the BBB, enhanced clearance of metabolites and protein fragments implicated in AD from the brain - an astrocyte-dependent mechanism primarily occurring during sleep [14] - and enhanced insulin signaling, suggested to play a role in AD [33], present additional mechanisms by which melatonin may impact AD pathology

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doi: 10.1620/tjem.224.209

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Documentation Requirements The operative report must clearly document the use of ICG dye, the ILM peel, air-fluid exchange, and the placement of C3F8 gas if performed in addition to a valid, covered diagnosis