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This dual potential of enhancing antioxidant defense and possibly boosting telomere integrity might explain some of the lifespan-extending actions hypothesized in epithalamin and Epithalon models

All procedures performed in studies involving human participants were in accordance with the ethical standards of the Institutional and/or National Research Committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards

Whilst peptidic inhibitors have been developed to weaken the integrity of the shelterin complex or target its interactions with partners, the direct modulation of protein interactions within shelterin using small molecules has been largely unexplored 12,13

10.3389/fimmu.2023.1239151 16 ChalmersJ

Medications like metformin or acid blockers can also play a role

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