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Mitochondria generate ROS as a by-product of the electron transport chain (ETC)
Adrijana Kekic References Sikiric P, Seiwerth S, Rucman R, et al
Peripheral immunity and risk of incident brain disorders: a prospective cohort study of 161,968 participants
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There is an inactivating point mutation in ALDH2 (named ALDH2*2) with low enzymatic activity [25]
