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Amongst the hundreds of components identified in the ECM, fibrous proteins and proteoglycans are the two main constituents (14,15)

This aligns with previous evidence linking insulin resistance and obesity with impaired testosterone production [14], implying that the metabolic improvements induced by GLP-1 therapy may restore androgen levels

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Fan Z, Wirth AK, Chen D, Wruck CJ, Rauh M, Buchfelder M, et al
