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Possible evidence of uveal melanoma shown with SDOCT is distortions of the retinal and sub-retinal profile, presence of intra and sub-retinal fluid, and abnormalities of the RPE such as atrophy, accumulations of lipofuscin, compression of the choriocapillaris, and presence of dome-shaped choroidal masses [62]

However, patients without hepatic metastasis had better ORR than patients with hepatic metastasis, indicating that ipi/nivo alone is not enough for LMUM [89]

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