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Dual agonism at the amylin receptor (a heterodimer of calcitonin receptor + RAMP1/2/3) and the calcitonin receptor in area postrema and arcuate nucleus, reducing food intake and promoting satiety

[DOI] [PubMed] [Google Scholar] 1301.Uc A, Kooy NW, Conklin JL, Bishop WP

The mean age (SD) was 46.5 (12.1) years

Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts

Mokhtari et al., 2011

The application of Gln in a mouse model of sepsis prevented apoptosis and the intestinal inflammatory response of intestinal intraepithelial lymphocyte (IEL) T cells and downregulated inflammation-related mediator genes expressed by IEL T cells, thereby reducing the extent of sepsis-induced intestinal epithelial injury (25, 26)