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"High frequency of vitamin B12 deficiency in asymptomatic individuals homozygous to MTHFR C677T mutation is associated with endothelial dysfunction and homocysteinemia"

Some of the roles that are attributed to vitamin B12 include: Forming red blood cells Playing a role in DNA/RNA synthesis Acting as a cofactor for methionine synthase (helping with methylation or the conversion of homocysteine to methionine, which protects cardiovascular health and more) Facilitating metabolic conversion of protein and fats Carrying out neurotransmitter functions and helping with production of hormones Helping convert amino acids and make creatine Producing myelin sheath (the coating of nerves) Helping with synthesis of hemoglobin Playing a role in fetal development during pregnancy How do you test my vitamin B12 levels to see if I need treatment

It is also important to ensure adequate folate levels through supplementation, if appropriate, once vitamin B12 supplementation has been commenced to avoid precipitating subacute combined degeneration of the spinal cord[2]

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The direction of human mesenchymal stem cells into the chondrogenic lineage is influenced by the features of hydrogel carriers

Toxicity induced by multiple high doses of vitamin B12 during pernicious anemia treatment: A case report