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GGT elevation promotes ROS generation and causes oxidative stress 27 , which seems to be involved in the occurrence of cardiovascular disease

Both the chaperone activity and the overall conformation of human PDI are redox-regulated

increased by excitatory 5-HT3 receptors (5HT3R) expressed in GABAergic interneurons, particularly in the amygdala 300 and hippocampus

doi: 10.1016/j.celrep.2019.02.037