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Chen H, Zheng Z, Kim KY et al (2016) Hypermethylation and downregulation of glutathione peroxidase 3 are related to pathogenesis of melanoma

Mucosal mast cells as key effector cells in food allergies

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They were identified approximately 27 years ago in yeast (14) and 25 years ago in mammals (15), and are functionally conserved in all three phylogenetic domains: Archaea, Bacteria and Eukaryota, stressing the importance of the existence of systems protecting against ROS for the evolution of living organisms (16) (Table I)

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The beneficial effects associated with reduced CD38 function can be primarily attributed to the consequent increase in NAD + levels and sirtuin activity