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coli proB , and the resulting strains were W303-1b/gsh1 ( GSH1 deletion), W303-1b/gsh1/pro1 ( GSH1::P gap - PRO1 - T pgk1 ) and W303-1b/gsh1/proB ( GSH1::P gap - proB - T pgk1 ) (Table 2)

Thus, GSH protects against the host immune defense and contributes to fitness of S

Tippmann, E

10.1016/j.neubiorev.2016.12.037 95

Other SOD1 mutants, including A4V, H46R, D90A and R115G, have been also found to disrupt proteostasis, diminish mitochondrial membrane potential and compromise ATP generation (Rasouli et al., 2018)

Concurrently, ROS-driven formation of 8-oxoG in DNA promotes epithelial-mesenchymal transition-associated transcriptional programs in epithelial cells [382]