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Cloyd, J

Curcumin and turmeric extracts are generally considered nontoxic and highly promising for various biological applications when administered at appropriate doses (50)

47 Taken together, these data suggest the reduced GSH/GSSG antioxidant capacity is insufficient to counter excessive OH production, and that unopposed OH can reach the nucleus to create the oxidative DNA adduct, 8-oxo-dG

This combination provides a temporal and spatial guarantee for the delivery of therapeutic agents, enhancing the potential of hydrogel-based systems for IVD regeneration and treatment

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Another peculiar characteristic of Grx2 is that it can cycle and receive electrons from thioredoxin reductase1 (TrxR1) [97]