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The second Cys, which prevents overoxidation of the active Cys by disulfide formation, is termed the resolving Cys. However, the pKas of the two Cys are not easily discerned from a protein structure and are generally determined experimentally

Selenium also promotes the proliferation and cytotoxic function of T cells, enhances antibody production by B cells, bolsters antiviral capability, and suppresses viral activity

Passive Targeting Passive targeting leverages the EPR effect, allowing nanoparticles to accumulate in inflamed joints due to leaky vasculature (7)

This is also the future direction of ferroptosis research (Li J

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