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However, it is crucial to note that comprehensive human safety data remains limited, as most research has been conducted in animal models, primarily rodents
That said, clinical experience has produced some rough approximations that providers use when switching patients
The 3DMM approach integrates information of several experimental conditions and replicates into one stoichiometry model, which uses phosphopeptide-, non-phosphorylated peptide- and corresponding protein-intensities from any multiplexed quantification method
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