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357,360 Similarly, administration of recombinant IL-6 and IL-6 overexpression results in decreased muscle mass in a cancer cachexia mouse model, 359 which can be alleviated by injecting IL-6 receptor antibodies
doi: 10.1093/ajcn/39.5.738
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Experts agree that supplementation is considered generally safe, even long-term

G.et al (2024)

0.9% saline (10 mL/kg) was administered intravenously to both the model and control groups

evaluated the plasma L-carnitine levels of subjects with high levels of TMAO ( n = 2,595) and found that the intake of large amounts of L-carnitine caused cardiovascular disease (CVD) and major adverse cardiac events (MI, stroke, or death)
