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In summary, MSCs offer a multifaceted approach to OA treatment by directly participating in cartilage repair and modulating the cytokine balance to suppress inflammation and promote anabolic processes

GSTP1 is a driver of triple-negative breast cancer cell metabolism and pathogenicity

Treatment of osteoarthritis by implantation of mg- and we43-cylinders - a preclinical study on bone and cartilage changes and their influence on pain sensation in rabbits

The phase 2 CENTAUR study and its open-label extension demonstrated the safety and efficacy of AMX0035 in PALS (7)

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Indeed, studies have shown that E2 regulates key modulators of lipid and glucose metabolism in adipose tissue, such as the reduction in lipoprotein lipase expression [144] and activity [145] in SAT from women, thereby limiting lipid uptake, while promoting lipolysis through upregulation of hormone-sensitive lipase [144]