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ITCs have been intensively studied for their biological activities, especially in mammals, where they are considered to have anticarcinogenic properties 12,13
2003;284:H1577H1584
598 FTH1 knockdown in neurons significantly inhibits cell viability and causes mitochondrial dysfunction, while overexpression of FTH1 impairs ferritinophagy, downregulates the expression of LC3 and NCOA4, and finally inhibits cell ferroptosis
10.1016/j.intimp.2015.05.024 193 ZhaoJ.LiG.ZhangY.SuX.HangC
When these cells have a steady supply of energy, they can better maintain the "tight junctions" between them
Kim et al., 2020
