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Pedditizi E, Peters R, Beckett N

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Our table of contents allows you to go straight to what interests you: Weight Loss Struggles | FAQs To know how GLP-1 medications work, it helps to understand why you cant lose weight in the first place

GLP-1R agonists (e.g., exendin-4 and liraglutide) reduce APP expression and processing in the brains of AD model mice through the activation of GLP-1R, decrease A protein production and plaque aggregation, and thus improve their spatial memory capacity ( 2.2 GLP-1R and tau protein hyperphosphorylation Hyperphosphorylated tau is a major component of intracellular neurofibrillary tangles (NFTs), which, together with amyloid plaques, are a distinguishing marker of AD (Figure 1)

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