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Values are expressed as mean standard deviation (SD) or mean standard error of the mean (SEM), as specified in the figure legends

doi: 10.1186/1471-2180-13-238 115 ChenMWeiWLiYGeSShenJGuoJet al
The number of reads in annotated genes was counted using htseq-count version 0.11.0 with option -i set to gene_id 74

DOI: 10.3389/fphys.2022.834597, Grndemann, D., Hartmann, L., and Flgel, S

IGF-1 LR3 offers numerous benefits including increased cell division, improved fat metabolism, enhanced muscle repair, and decreased insulin dependence

Because peripheral insulin sensitivity differences could confound these observations, the authors validated in mice that female islets upregulate the UPR pathway and resist ER stress, mirroring human findings
