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Nonetheless, the role of other upstream signaling pathways cannot be excluded

It has been postulated that the advance of amyloid build-up could act as an antimicrobial defense mechanism, reducing viral and bacterial spreading, by catching invading pathogens [40]

Cardioprotective effect of modified peroxiredoxins in retrograde perfusion of isolated rat heart under conditions of oxidative stress

doi: 10.1007/s11033-021-06889-7

These alterations are the probable result of the lengthy cellular damage induced by MTX resulting in increased levels of ROS leading to DNA injury, oxidation, and proliferation inhibition

10.1016/j.redox.2015.08.006 98 MatsushitaM.FreigangS.SchneiderC.ConradM.BornkammG
