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Description
For the Revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R), a mean slope of 1.0 was observed in the treated group compared to 1.4 in the untreated patients ( p = 0.0575)

9.4.5 Overall assessment In conclusion, every method has benefits and drawbacks and yields data that vary significantly
Song and co-workers used cell stimulation with epidermal growth factor (EGF) as an example of the physiological stimulus which may trigger PLC activation

PMC 3666194

However, treating the PVCs can reverse the problem

Shaikh, Malliga E