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Once B12 has been released from dietary proteins, it binds to salivary haptocorrina, a binding protein (also called protein R or cobalofilin) secreted in the salivary glands and binds in the stomach with cobalamin, which has a high affinity for this protein, forming a complex with it as it passes into the duodenum

Therefore, the development of novel and versatile methodologies for modifying AONs with precise control over these critical features remains a significant endeavour 23

Mazahir et al

[DOI] [PubMed] [Google Scholar] 125.Armstrong JS, Jones DP

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