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In support of a role for the GPx-1 polymorphisms in breast cancer risk, a nested casecontrol study from Denmark found that Leu carriers ( i.e heterozygous, Leu/Pro, plus homozygous, Leu/Leu) had significantly increased risk of breast cancer compared to Pro/Pro homozygotes (301)

alpha-Tocopherol in human spermatozoa and seminal plasma: Relationships with motility, antioxidant enzymes and leukocytes

In the same study, both top and bottom quintiles of plasma betaine concentrations were associated with an increased risk of secondary acute myocardial infarction

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blood brain barrier and placenta (Wakatsuki et al., 1999)

Thus, the BTBR model is currently a good choice for studying the pathogenesis of ASD