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doi: 10.3390/ph16081074

Peripheral patterns of calcitonin-gene-related peptide general somatic sensory innervation: cutaneous and deep terminations

Cell 125, 509522

Hydrogen bonds, however, are distinct from dipoledipole interactions for two main reasons: (1) fluorine, oxygen, and nitrogen are highly electronegative, so the partial charges involved are large, and (2) the hydrogen atom is very small, which allows the partial positive charge on hydrogen to be very close to the partial negative charge on the H-bond acceptor

All of these limitations are relevant to HGF

Studies also reveal that doxorubicin enhances the expression of SASP, thereby inducing inflammatory states in p16-3MR cells [60]