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4.2 Bioactive compounds boost antioxidant and anti-inflammatory responses by activating Nrf2/KEAP1 signaling to combat mastitis: in vivo evidence Recent in vivo studies have demonstrated that bioactive compounds can significantly enhance antioxidant and anti-inflammatory responses by activating the Nrf2/KEAP1 signaling pathway, offering a promising therapeutic approach for combating mastitis

Footnotes Conflict of interest: None declared Declaration of Figures Authenticity: All figures submitted have been created by the authors, who confirm that the images are original with no duplication and have not been previously published in whole or in part

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Immunol 46:8288 [DOI] [PMC free article] [PubMed] [Google Scholar] 23.Powell JD, Pollizzi KN, Heikamp EB, Horton MR

doi: 10.1590/s0102-865020180110000002

Stimulation of the target gene, CRD-BP (Coding Region Determinant-Binding Protein, an RNA-binding protein), by activated -catenin stabilizes mRNA of TrCP (Beta-transducin repeat-containing protein) [86]