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Until recently, it was commonly believed that the synthesis of vitamin B12 by the bodys own intestinal bacteria is of little importance from the point of view of its availability to this organism, because it takes place outside the main area of active intestinal absorption of this vitamin [4,34]

Sociodemographic characteristics Diagnosis (vitamin B12 deficiency or pernicious anaemia), age, sex, education level, employment status, country of residence (England, Wales, Scotland, Northern Ireland, Republic of Ireland), region of residence (nine English regions, according to the Office for National Statistics, Wales, Scotland, and Northern Ireland) were assessed using the questions in Supplementary Table S1

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