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Conclusion: The Case for Informed Experimentation NAD+ IV therapy sits in an interesting position in the longevity medicine landscape: past the purely speculative phase, but not yet definitively validated by large-scale clinical trials

The significance of this paper is not only to compare the three routes of administration but also to evaluate them and determine which route is the best to administrate the drug

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doi: 10.1016/j.mayocp.2019.08.029 [PubMed] 32571502 Chhabria M, Portales-Castillo I, Chowdhury M, Sohail A, Sanchez-Tejera D, Bress J, Sterns RH

Of these 32 semaglutide-treated patients that developed anti-semaglutide antibodies, 19 patients (0.6% of the overall population) developed antibodies cross-reacting with native GLP-1

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