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The PCA was weighted by group size

Pattern across both trials Nausea, vomiting, and diarrhea peaked during dose escalation and tapered during maintenance

10.1016/j.plaphy.2016.05.012 Plant Physiol

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

But using both in a safe routine usually gives you the best results
