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You do not need a long wait, just enough that the serum is not pooling on the surface when the cream goes on

Preincubation with NAC was able to prevent HNE and A-induced HNE addition to neprilysin and thus maintain neprilysin activity [64]

For instance, its important that all equipment used for reconstitution is sterilized prior to use and only sterile bottles should be utilized for storage purposes

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