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A randomized double-blind comparison

However, while they are recognized for their skin-lightening and brightening effects, the outcomes can vary and are not always predictable

Toumi et al., 2021)

NO can diffuse widely (~400 m) [78] and react with superoxide to form peroxynitrite, which is a potent oxidant [73]

The antitumor activity of NGR-TNF- was also studied in combination with various chemotherapeutic drugs: doxorubicin and melphalan as well as cisplatin, paclitaxel, and gemcitabine and compared to the efficacy of the chemotherapeutic drugs alone in various murine tumor models [105]

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