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10.1038/nbt.4273 Nat

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Cellular and porcine models were used to evaluate the safety of microneedle-assisted copper peptide delivery

TGF1-induced K447 lactylation is essential, while SIRT2 delactylates USP2 to suppress its activity

Mutations in either the HAMP gene, which encodes the synthesis of hepcidin, or the HFE2 gene, which encodes hemojuvelin, a protein important in the regulation of iron homeostasis, characterize type 2 hereditary hemochromatosis, which is important in the development of cardiac and endocrine disorders

All these essential enzymes are closely related to the pathogenesis and drug resistance of mycobacteria
