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NADPH is required for the regeneration of reduced glutathione, which neutralizes reactive oxygen species (ROS) and prevents cellular damage

Cell growth assays Cell proliferation was measured by counting cells after trypsinization in 2D cultures

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Thus, Cys availability (and therefore sulfur) will impact biosynthesis of all three, while levels of SAM will affect EGT and gliotoxin biosynthesis

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Calcium channel blockers, which regulate Ca influx into cells, improved social behavior in mice ASD models