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Vitamin C mechanisms involve serving as enzymatic cofactor for collagen hydroxylation and providing direct antioxidant protection, creating effects requiring ongoing application for maintaining antioxidant benefits but potentially supporting durable collagen improvements if used sufficiently long

[PubMed 3680403] 1301

Kudva, P., Tawkhira, S

With traditional therapies such as 131 I therapy, surgery treatment and TSH suppression drugs developing for a long period, metabolism-based therapy has progressed much

Although the current evidence is very promising, there are still some knowledge gaps that should be addressed to further clarify the exact mechanisms linking NNMT to obesity and T2D and to develop clinical drugs targeting NNMT

[DOI] [PubMed] [Google Scholar] 162.Desole MS, Miele M, Demontis P, Carboni F, Senini A, Esposito G, Anania V