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PRELIMINARY RESULTS OF A PHASE I/II STUDY OF AZACITIDINE, VENETOCLAX AND PEVONEDISTAT IN PATIENTS WITH SECONDARY ACUTE MYELOID LEUKEMIA WHO ARE UNFIT FOR INTENSIVE CHEMOTHERAPY

XL: Conceptualization, Data curation, Resources, Software, Writing original draft, Writing review & editing

12 (2), 205 (2022) A

doi:10.1073/pnas.2336090100

Intramuscular injections (often into the thigh or upper arm) ensure your body gets the full benefit without any loss

41 Slc3a2-dependent BCAA metabolism also has a key role in the physiological activities of Foxp3 + Treg cells, and either BCAA deprivation or SLC3A2 mutation can induce impaired activation of the mTORC1 pathway in Treg cells and inhibit the immunosuppressive function of Treg cells