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Tumor heterogeneity in glioblastomas: from light microscopy to molecular pathology

Metabolism One of MTXs main metabolites, 7-hydroxymethotrexate (7-OH-MTX), is produced by the liver during the first-pass metabolism of MTX (Seideman et al

Olive oil polyphenols reduce oxysterols -induced redox imbalance and pro-inflammatory response in intestinal cells

Chromatin organization Glutamine metabolism does not only generate building blocks and energy for cell growth, but also produces co-substrates for cellular regulatory cascades, including those that regulate chromatin organization

A one-step RT-qPCR kit was used to reverse transcribe the RNA into the first-strand cDNA (Takara, Shanghai, China)

Cancer 20 , 17386 (2013)