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LTR was found to inhibit WNT/-catenin signaling in alveolar epithelial progenitor cells by activating non-canonical NF-B signaling, thereby promoting lymphocyte apoptosis and inhibiting regeneration

An increased expression of the killer-type T cells also leads to an induction of autoimmune responses [1]

AoyamaNThebergeJDrostDJManchandaRNorthcottSNeufeldRWet al

[DOI] [PubMed] [Google Scholar] Slifstein Mvan de Giessen EVan Snellenberg JThompson JLNarendran RGil RHackett EGirgis ROjeil NMoore H, et al

[DOI] [PubMed] [Google Scholar] 126.Kornblihtt L.I., Finocchiaro L., Molinas F.C

Still, when they co-occur on opposing strands, BER can lead to the generation of double-stranded DNA breaks (41)
