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The data are displayed as means with standard deviations

Methylcobalamin, a form of B12, is particularly essential for synthesizing neuronal lipids, regenerating axonal nerves, and exerting neuroprotective effects, potentially improving conditions such as Alzheimer's disease, Parkinsonism, and dementia, while also serving as an approved treatment for peripheral neuropathy

It exists in two forms: oxidized glutathione disulfide (GSSG), which is reduced as a tripeptide gamma-glutamyl-cysteinyl-glycine (GSH)

Table 3 Clinical trials involving N-acetylcysteine in Alzheimers disease (AD) and mild-cognitive impairment (MCI)

8 , 42 Prior work by Abdel-Rahman et al

A better knowledge of MTXs molecular mechanisms of action could aid in the explanation of many toxicities associated with the drug (Tian and Cronstein 2007)