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10.1016/j.pmpp.2008.04.003 89 LeeY

10.3390/ijerph10093886 159 ValkoM.LeibfritzD.MoncolJ.CroninM

Bottom: volcano plot showing relative fold change (log 2 ) in whole cell metabolite abundance versus log 10 (P value) from ER-tag HEK293T cells treated with glucose deprivation compared to glucose repletion

Finally, ALA/GLA demonstrated notable efficacy in reducing symptoms and functional deterioration measured by the Hi-Ob scale (a historical-objective scale based on clinical history and physical examination), while the multivitamin group showed a less marked improvement