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10.1016/j.niox.2024.11.009 174 YuanX

Ther Use Med Plants Extracts: Volume 2: Phytochem Bioact Compd 2:25164 Neag MA, Mocan A, Echeverra J, Pop RM, Bocsan CI, Crian G et al (2018) Berberine: Botanical occurrence, traditional uses, extraction methods, and relevance in cardiovascular, metabolic, hepatic, and renal disorders

Due to the challenges of solving the crystal structure of a selenium-containing protein, there are limited wild-type crystal structures for human GPX4 available
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It is depleted in Parkinson's patients, which may accelerate neurodegeneration

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