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In that context, it is noteworthy that optimal function of stem cells depends on their highly specialized microenvironment, or niche [30, 31], and SASP factors deleteriously affect stem cells by altering this niche [32, 33]

The arginine salt form offers enhanced solubility and oral stability, making it ideal for nutritional applications

While this is beneficial for healing, angiogenesis also supports tumor growth and metastasis

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Why Does This Occur

Less commonly, patients develop pretibial dermopathy and acropachy, reflecting fibroblast activation in the skin and extremities [21]