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Figure 3 2.1 Cellular senescence and ageing Cellular senescence, characterized by irreversible exit from the cell cycle and entry into a state of growth arrest, was initially proposed by Hayflick and Moorhead in the 1960s ( in vitro , is now recognized as a response to various stressors, including telomere shortening, oxidative stress, and chromatin structure abnormalities ( WAF1/CIP1 or p16 INK4a /Rb signaling pathway

Polymer 2017(114):242248 Sanz-Horta R, Elvira C, Gallardo A, Reinecke H, Rodrguez-Hernndez J (2020) Fabrication of 3D-printed biodegradable porous scaffolds combining multi-material fused deposition modeling and supercritical CO2 techniques

Potential clinical benefits of quercetin in the early stage of COVID-19: Results of a second, pilot, randomized, controlled, and open-label clinical trial