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SEM analysis performed on three powder samples (Fe 3 O 4 , MSN, MSN-PTA) revealed no aggregation in the final syntheses, indicating well-dispersed nanoparticles in the final products

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Secondary PK endpoints included the total area under the serum concentration-time curve extrapolated to infinity (AUC 0- ), time to reach C max (t max ), terminal elimination half life (t 1/2 ), apparent volume of distribution (V z/f ) and apparent clearance (CL/f)

Direct NAD+ administration vs precursors (NMN, NR) This is a frequent question in research