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This effect effectively inhibits downstream MyD88-dependent signal transduction, reduces the phosphorylation of the NF-Bp65 subunit and blocks its nuclear translocation, and ultimately significantly downregulates the expression of inflammatory mediators such as COX-2 and iNOS, as well as pro-inflammatory factors such as IL-6 and TNF-

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This ingredient is also calming with anti-inflammatory and mild antimicrobial activity, making it a great pick for sensitive, irritated, or post-sun skin