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For instance, children with severe vitamin E deficiency from birth and are not treated with vitamin E rapidly develop neurological symptoms

Administration of NRF2 activator, which would be favorable for reinvigorating anti-tumor immunity and conferring the metabolic liabilities on cancer cells, in combination with inhibitors of glutamate and/or NEAA synthesis may be an effective anti-tumor therapy from the viewpoint of interaction between cancer cells and their microenvironment

Malfait F, Symoens S, De Backer J, et al

[4] Oral glucose tolerance evaluation across the pooled trial population indicated that, in contrast to intact hGH, AOD-9604 did not appear to interact with carbohydrate metabolism negatively

Large reports have shown natural products have strong therapeutic values in promoting mitochondrial biogenetics and energetics, reducing mitochondrial ROS, enhancing mitophagy, and regulating mitochondrial dynamics (Mu et al., 2020