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Standard care is applied per guidelines, followed by a screen for contraindications and drugdrug interactions

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This metabolic reprogramming induces the typical Warburg effect, which manifests as enhanced lactate production as an energy source even under normoxic conditions, rather than the more efficient mitochondrial oxidative phosphorylation pathway, changing the energy metabolism pattern of tumor cells and leading to energy metabolism imbalance in tumor cells

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Gout is a disease that affects mainly males, with a clear increase in prevalence in both sexes with aging, and is caused by the tissue deposition of urate crystals that elicit an intense self-limiting inflammatory reaction